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Prospec/SERPINA5 Human/Serpin Peptidase Inhibitor Clade A Member 5 Human Recombinant/10µg/PRO-749-10µg-10µg

Catalogue number
PRO-749
Synonyms
PAI3, PCI, PROCI, PLANH3, Protein-C Inhibitor, Serpin A5, Plasminogen activator inhibitor 3, PAI-3, SERPINA5.
Introduction
SERPINA5 up regulates TAFI activation by inhibiting the protein C activation. SERPINA5 is a significant regulator in the equilibrium between coagulation and fibrinolysis by differentially inhibiting the activation of TAFI and of Protein-C. SERPINA5 belongs to the serpin serine proteinase inhibitor family. SERPINA5 protein inhibits plasminogen activators as well as activated protein C.SERPINA5 is secreted in plasma & liver. SERPINA5 is involved in cell inflammation, proliferation, apoptosis, tumour cell migration, invasion, and metastasis. Moreover, SERPINA5 controls the invasive potential of renal cell carcinoma by inhibiting urinary plasminogen activator secreted by the cells. SERPINA5participtesin regulating key serine proteases which are involved in metastatic prostate disease.
Description
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Safety Data Sheet
SDS