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Other_recombinant_protein >
Prospec/PDCD5 Human/Programmed Cell Death-5 Human Recombinant/20µg/PRO-624-20µg-20µg
Cataloguenumber
PRO-624
Synonyms
Introduction
PDCD5isexpressedintumorcellsduringapoptosisindependentoftheapoptosis-inducingstimuli.Priortoapoptosisinduction,PDCD5isdistributedinboththenucleusandcytoplasm.Onceapoptosisisinduced,theamountofPDCD5increasesandbyrelocationfromthecytoplasm,itaccumulatesinthenucleus.PDCD5proteinhasastablehelicalcoreconformationconsistingofatriple-helixbundleandtwodissociatedterminalregions.PDCD5isanimportantnovelproteinthatregulatesbothapoptoticandnon-apoptoticprogrammedcelldeath.PDCD5functionsintheprocessofapoptosis.PDCD5playsanimportantroleinregulationofapoptoticprocessesingastriccancercellsandgastrictumors.PDCD5playsaroleinthepathogenesisofrheumatoidarthritis.-27G/-11ASNPisassociatedwithreducedPDCD5promoteractivityandincreasedsusceptibilitytochronicmyelogenousleukemia.PDCD5genemaybeatargetgeneunderthecontrolofsomeimportantapoptosis-relatedtranscriptionalfactorsduringthecellapoptosis.
Description
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PhysicalAppearance
Formulation
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SafetyDataSheet
SDS