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Prospec/PVALB Rat/Parvalbumin Rat Recombinant/2µg/PRO-398-2µg-2µg
Prospec/PVALB Rat/Parvalbumin Rat Recombinant/2µg/PRO-398-2µg-2µg
商品编号：
PRO-398-2µg-2µg
品牌：
prospecbio
市场价：
¥1000.00
美元价：
450.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PRO-398
Synonyms
Pvalb, Pva, PALB1, Parvalbumin.
Introduction
Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs and is structurally related to calmodulin and troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain and some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier and basket cells in the cortex. Parvalbumin interneurons" connections are generally perisomatic (surrounding the cell body of neurons). In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, and oriens-lacunosum moleculare (O-LM) cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, and are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin and GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia. Parvalbumin is identified as an allergen causing seafood allergy. Pvalb may have evolved from an ancestral four domain calcium binding protein.
Description
Recombinant Rat Parvalbumin produced in E.Coli.The Rat Parvalbumin is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The protein was lyophilized from a concentrated solution (1mg/ml) without any additives.
Solubility
It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Applications
The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay and intracellular injection.For fluid-phase adsorption in immunohistochemistry we suggest the following procedure:A- Dilute 1 µl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry (final dilution 1:5"000).B- Add 1µg of the Parvalbumin to 1ml of the diluted antibody solution and mix well.C- Incubate for at least 6 hours in the cold.D- Apply to tissue-sections and incubate for 3 days.E- Complete the immunohistochemical reaction as usual (biotinylated second antibody, ABC-complex, DAB).As a result, the immunostaining should be strongly reduced or even completely prevented.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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