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Other_recombinant_protein >
Prospec/SPARCL1 Mouse/SPARC Like 1 Mouse Recombinant/2µg/PRO-2617-2µg-2µg
Cataloguenumber
PRO-2617
Synonyms
Sparcl1,Ecm2,hevin,mast9,Sc1,SPARC-likeprotein1,Extracellularmatrixprotein2,MatrixglycoproteinSc1.
Introduction
SPARC-likeprotein1orSPARC1isananti-adhesiveproteinwithasimilaritytotheSPARCprotein’sstructure.SPARC1ishighlyexpressedinseveraltissuessuchasbrain,lungs,kidney,heart,althoughitisnotfoundinthelivertissue.TheproteininhibitsspreADIngoradhesionofmanysubstratesandisconsideredtoleadtoantiadhesivesignalingthatstopsneuronalmigration,thatoccursduringdevelopmentorasatraumaresponse,consistentwithproductionbyglialandneuronalcells.
Description
SPARCL1MouseRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining642aminoacids(17-650a.a)andhavingamolecularmassof71.7kDa.SPARCL1isfusedtoan8aminoacidHis-tagatC-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
SPARCL1proteinsolution(0.25mg/ml)containingPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
IPTSTRFLSDHSNPTTATLVTPEDATVPIAGVEATADIENHPSDKAEKPSALNSEEETHEQSTEQDKTYSFEVDLKDEEDGDGDLSVDPTEGTLTLDLQEGTSEPQQKSLPENGDFPATVSTSYVDPNQRANITKGKESQEQPVSDSHQQPNESSKQTQDLKAEESQTQDPDIPNEEEEEEEDEEEEEEEEPEDIGAPSDNQEEGKEPLEEQPTSKWEGNREQSDDTLEESSQPTQISKTEKHQSEQGNQGQESDSEAEGEDKAAGSKEHIPHTEQQDQEGKAGLEAIGNQKDTDEKAVSTEPTDAAVVPRSHGGAGDNGGGDDSKHGAGDDYFIPSQEFLEAERMHSLSYYLKYGGGEETTTGESENRREAADNQEAKKAESSPNAEPSDEGNSREHSAGSCTNFQCKRGHICKTDPQGKPHCVCQDPETCPPAKILDQACGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPACTDFEVAQFPLRMRDWLKNILMQLYEPNPKHGGYLNEKQRSKVKKIYLDEKRLLAGHPIELLLRDFKKNYHMYVYPVHWQFNELDQHPADRILTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLFLEHHHHHH
SafetyDataSheet
SDS