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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prospec/FURIN Human/Furin Human Recombinant/5µg/PRO-2199-5µg-5µg
商品详细Prospec/FURIN Human/Furin Human Recombinant/5µg/PRO-2199-5µg-5µg
Prospec/FURIN Human/Furin Human Recombinant/5µg/PRO-2199-5µg-5µg
Prospec/FURIN Human/Furin Human Recombinant/5µg/PRO-2199-5µg-5µg
商品编号: PRO-2199-5µg-5µg
品牌: prospecbio
市场价: ¥1000.00
美元价: 450.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

PRO-2199

Synonyms

Furin(Paired Basic Amino Acid Cleaving Enzyme), PCSK3, PACE, FUR, Paired Basic AminoAcid Residue-Cleaving Enzyme, EC 3.4.21.75, Paired Basic Amino Acid CleavingEnzyme (Furin, Membrane Associated Receptor Protein), Proprotein ConvertaseSubtilisin/Kexin Type 3, Furin, Membrane Associated Receptor Protein, DibasicProcessing Enzyme, Dibasic-Processing Enzyme, FES Upstream Region, EC 3.4.21, Furin,SPC1, Dibasic-processing enzyme, Paired basic amino acid residue-cleavingenzyme.

Introduction

Furinis a member of the peptidase S8 family. Furin signifies the ubiquitousendoprotease activity within constitutive secretory pathways aswell as capable of cleavage at the RX (K/R) R consensus motif. Furin is considered to be one of the proteases responsiblefor the activation of HIV envelope glycoproteins gp160 as well as gp140 andmight take part in tumor progression. Among the diseases associated with FURINare dementia, familial british and plague.

Description

FURIN Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 645 amino acids (108-715 a.a) and having amolecular mass of 69.8kDa.
FURIN is fused to a 37amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

FURINprotein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by SDS-PAGE.

Amino acid sequence

MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDVY QEPTDPKFPQ QWYLSGVTQR DLNVKAAWAQ GYTGHGIVVSILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNARIGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFVWASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKCTESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLDAGAMVALAQN WTTVAPQRKC IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGDLAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE IENTSEANNY GTLTKFTLVLYGTAPEGLPV PPESSGCKTL TSSQACVVCE EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASVCAPCHASCAT CQGPALTDCL SCPSHASLDP VEQTCSRQSQ SSRESPPQQQ PPRLPPEVEA GQRLRAGLLPSHLPE.

Safety Data Sheet

SDS

Usage

Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.