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Prospec/FETUB Human/Fetuin-B Human Recombinant/2µg/PRO-1586-2µg-2µg
Prospec/FETUB Human/Fetuin-B Human Recombinant/2µg/PRO-1586-2µg-2µg
商品编号：
PRO-1586-2µg-2µg
品牌：
prospecbio
市场价：
¥1000.00
美元价：
450.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PRO-1586
Synonyms
Fetuin-B, 16G2, Fetuin-like protein IRL685, Gugu, FETUB, IRL685.
Introduction
Fetuin-B (FETUB) belongs to the fetuin family, part of the cystatin superfamily proteins and comprised of 2 cystatin domains. Fetuin-B is found in a secreted form in the serum, it is expressed in the liver, tongue and placenta. FETUB regulates osteogenesis by inhibition effect on mineralization. Fetuins are implicated in a number of various functions, including osteogenesis and bone resorption, regulation of the hepatocyte growth factor receptors, and response to systemic inflammation. FETUB also has a role in oocyte maturation. Fetuin-B is essential in preventing premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, which is a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening.
Description
Fetuin-B Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain containing a total of 377 amino acids, having a molecular mass of 41.8kDa (calculated) though it migrates at approximately 55kDa on SDS PAGE, the Fetuin-B is also composed of a 4 a.a N-terminal linker and fused to a 6 a.a His tag at C-Terminus.The Human FETUB is purified by proprietary chromatographic techniques.
Source
HEK 293.
Physical Appearance
Filtered White lyophilized (freeze-dried) powder.
Formulation
FETUB filtered (0.4µm) and lyophilized from 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4.
Solubility
It is recommended to add deionized water to a working concentration of 0.5mg/ml and let the lyophilized pellet dissolve completely. FETUB is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
HSHVCGAMSP PQLALNPSAL LSRGCNDSDV LAVAGFALRD INKDRKDGYV LRLNRVNDAQ EYRRGGLGSL FYLTLDVLET DCHVLRKKAW QDCGMRIFFE SVYGQCKAIF YMNNPSRVLY LAAYNCTLRP VSKKKIYMTC PDCPSSIPTD SSNHQVLEAA TESLAKYNNE NTSKQYSLFK VTRASSQWVV GPSYFVEYLI KESPCTKSQA SSCSLQSSDS VPVGLCKGSL TRTHWEKFVS VTCDFFESQA PATGSENSAV NQKPTNLPKV EESQQKNTPP TDSPSKAGPR GSVQYLPDLD DKNSQEKGPQ EAFPVHLDLT TNPQGETLDI SFLFLEPMEE KLVVLPFPKE KARTAECPGP AQNASPLVLP PHHHHHH.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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