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主营:主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prospec/FCER1A Human/Fc-Epsilon RI-Alpha Human Recombinant/5µg/PRO-1741-5µg-5µg
商品详细Prospec/FCER1A Human/Fc-Epsilon RI-Alpha Human Recombinant/5µg/PRO-1741-5µg-5µg
Prospec/FCER1A Human/Fc-Epsilon RI-Alpha Human Recombinant/5µg/PRO-1741-5µg-5µg
Prospec/FCER1A Human/Fc-Epsilon RI-Alpha Human Recombinant/5µg/PRO-1741-5µg-5µg
商品编号: PRO-1741-5µg-5µg
品牌: prospecbio
市场价: ¥1000.00
美元价: 450.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

PRO-1741

Synonyms

Fc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A, IgE Fc Receptor Subunit Alpha, FcERI, Fc-Epsilon RI-Alpha, Fc Epsilon RIAlpha-Chain, Fc IgE Receptor, Alpha Polypeptide, High Affinity ImmunoglobulinEpsilon Receptor Alpha-Subunit, High Affinity Immunoglobulin Epsilon ReceptorSubunit Alpha, Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, AlphaPolypeptide.

Introduction

Fcfragment of IgE, high affinity I, receptor for; alpha polypeptide (FCER1A)binds to the Fc region of immunoglobulins epsilon. FCER1A is a high affinityreceptor. In addition FCER1A is responsible for starting the allergic response.Binding of allergen to receptor-bound IgE leads to cell activation and therelease of mediators such as histamine which is responsible for themanifestations of allergy. This receptor is contains of an alpha subunit, abeta subunit, and two gamma subunits. FCER1A stands for the alpha subunit.Among the diseases associated with FCER1A are mast-cell leukemia, and allergicasthma.

Description

FCER1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (26-205aa) and having a molecular mass of 23.4kDa.
FCER1A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

FCER1A protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

Purity

Greater than 85% as determined by SDS-PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSVPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSEETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYKVIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.