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Prospec/CGB3 Human/CGB3 Human Recombinant/50µg/PRO-2398-50µg-50µg

Cataloguenumber
PRO-2398
Synonyms
CGB3CGB5CGB8,CGB5,CGB7,CGB8,HCGB,CG-beta.
Introduction
CGB3,belongstotheglycoproteinhormonebetachainfamily.CGB3encodesthebeta3subunit.CGB3stimulatestheexpressionofGCM1targetgenes,aswellasthefusogenicproteinsyncytin-1,topromoteplacentalcellfusion.FurThermore,CGB3issynthesizedinlargequantitiesbythegrowingplacenta,reachingpeakconcentrationsinmaternalbloodthroughoutthelatefirsttrimesterandearlymid-trimesterofpregnancy.CGB3isexpressedsolelybytrophoblasts.CGB3isasignificantbioMarkerinpregnancyandoncology,whereitisroutinelydetectedandquantifiedbyspecificimmunoassays.
Description
CGB3HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining154aminoacids(21-165.a.)andhavingamolecularmassof16.6kDa(MolecularsizeonSDS-PAGEwillappearatapproximately18-28kDa).CGB3isexpressedwitha6aminoacidHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CGB3proteinsolution(0.25mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
SafetyDataSheet
SDS
Aminoacidsequence
ADPSKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQHHHHHH.