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Prospec/BTN3A1人类/丁酰肌醇亚家族3成员A1人类重组/1µg/PRO-2454-1µg-1µg
Cataloguenumber
PRO-2454
Synonyms
ButyrophilinSubfamily3MemberA1,BTF5,DJ45P21.3(Butyrophilin,Subfamily3,MemberA1),Butyrophilin,Subfamily3,MemberA1,CD277Antigen,BTN3.1,BT3.1,CD277,Butyrophilinsubfamily3memberA1.
Introduction
Butyrophilinsubfamily3memberA1,alsoknownasBTN3A1isamemberoftheimmunoglobulinsuperfamily.BTN3A1iscomposedofanextracellularN-terminalIgVaswellasamembraneproximalIgCdomainfollowedbyatransmembranedomainandalsoacytoplasmictail.BTN3A1participatesinT-cellactivationandalsointheadaptiveimmuneresponse.FurThermore,BTN3A1regulatestheproliferationofactivatedT-cells&thereleaseofcytokinesandIFNGbyactivatedT-cells.BTN3A1,MediatestheresponseofT-cellstoinfectedaswellastransformedcellswhicharecategorizedbyhighlevelsofphosphorylatedmetabolites,suchasisopentenylpyrophosphate.
Description
BTN3A1HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining464aminoacids(30-254a.a.)andhavingamolecularmassof51.1kDa(MolecularsizeonSDS-PAGEwillappearatapproximately50-70kDa).BTN3A1isexpressedwitha239aminoacidhIgG-HisTagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
BTN3A1proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
QFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS