>
产品中心 >
Other_recombinant_protein >
Prospec/KLRD1 Human/Killer Cell Lectin Like Receptor D1 Human Recombinant/1µg/PRO-2483-1µg-1µg
Cataloguenumber
PRO-2483
Synonyms
KillerCellLectinLikeReceptorD1,KillerCellLectin-LikeReceptorSubfamilyD,Member1,NKCellReceptor,CD94Antigen,CD94,KP43,KillerCellLectin-LikeReceptorSubfamilyDMember1,NaturalKillerCellsAntigenCD94,KLRD1.
Introduction
KLRD1,alsoknownasKillerCellLectinLikeReceptorD1,isexpressedonthesurfaceofnaturalkillercellsintheinnateimmunesystem.KLRD1functionsasareceptorfortherecognitionofMHCclassIHLA-EmoleculesbyNKcellsandsomecytotoxicT-cells.KLRD1cancreatedisulfide-bondedheterodimerwithNKG2familymembers.CD94&NKG2complexinteractswith(HLA)-E,HumanLeukocyteAntigenontargetcellsonthesurfaceofnaturalkillercells.
Description
KLRD1producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechain(32-179a.a.)andfusedtoa6aaHisTagatC-terminuscontainingatotalof157aminoacidsandhavingamolecularmassof18.2kDa.KLRD1showsmultiplebandsbetween18-28kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
KLRD1proteinsolution(0.5mg/ml)containsPhosphatebufferedsaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLIHHHHHH
SafetyDataSheet
SDS

