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Prospec/JAM2 Human, Sf9/Junctional Adhesion Molecule 2 Human Recombinant, Sf9/2µg/PRO-2509-2µg-2µg
Cataloguenumber
PRO-2509
Synonyms
JunctionalAdhesionMolecule2,VascularEndothelialJunction-AssociatedMolecule,C21orf43,VE-JAM,JAM-2,JAM-B,VEJAM,JunctionalAdhesionMoleculeB,JAM-IT/VE-JAM,CD322Antigen,PRO245,CD322,JAMB,JunctionaladhesionmoleculeB.
Introduction
JunctionalAdhesionMolecule2(JAM2)isamemberoftheimmunoglobulinsuperfamily,andthejunctionaladhesionmolecule(JAM)family.JAM2isatypeImembraneproteinwhichislocalizedatthetightjunctionsofbothepithelialandendothelialcells.JAM2functionsasanadhesiveligandforinteractingwithvariousimmunecelltypes,andmayhavearoleinlymphocytehomingtosecondarylymphoidorgans.
Description
JAM2producedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining452aminoacids(29-238a.a.)andhavingamolecularmassof50.7kDa.(MolecularsizeonSDS-PAGEwillappearatapproximately50-70kDa).JAM2isexpressedwitha239aminoacidhIgG-His-tagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
JAM2proteinsolution(0.5mg/ml)contains50%glycerol,1mMDTT&PhosphateBufferedSaline(pH7.4).
StABIlity
Purity
Aminoacidsequence
ADPFSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS