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Prospec/ITGB1 Human, Sf9/Integrin Beta 1 Human Recombinant, Sf9/1mg/PRO-2410-1mg-1mg

Cataloguenumber
PRO-2410
Synonyms
Integrinbeta-1,Fibronectinreceptorsubunitbeta,GlycoproteinIIa,GPIIA,VLA-4subunitbeta,CD29,ITGB1,FNRB,MDF2,MSK12,Integrinbeta1,CD29,VLAB.
Introduction
Integrinsareheterodimericproteinsconsistofalphaandbetasubunits.Therearemorethan18alphaand8betasubunitsdiscoveredinmammals.Integrinfamilymembersaremembranereceptorsthatparticipatesincelladhesionandrecognitioninavarietyofprocessesincludingembryogenesis,hemostasis,tissuerepair,immuneresponseandmetastaticdiffusionoftumorcells.ITGB1encodesabetasubunit.
Description
ITGB1HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining716aminoacids(1-728)andhavingamolecularmassof79.4kDa(MolecularsizeonSDS-PAGEwillappearatapproximately70-100kDa).ITGB1isfusedtoan8aminoacidHis-TagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
ITGB1proteinsolution(1.0mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
QTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPDLEHHHHHH
SafetyDataSheet
SDS