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Prospec/EFNA3 Human, Sf9/Ephrin A3 Human Recombinant, Sf9/20µg/PRO-2614-20µg-20µg
Cataloguenumber
PRO-2614
Synonyms
Ephrin-A3,EFL2,Ehk1-L,EPLG3,LERK3,EPH-relatedreceptortyrosinekinaseligand3.
Introduction
EFNA3belongstotheephrin(EPH)family.TheephrinsandEPH-relatedreceptorsincludethelargestsubfamilyofreceptorprotein-tyrosinekinaseswhichhavebeenimplicatedinmediatingdevelopmentalevents,especiallyinthenervoussystemandinerythropoiesis.Ephrinsaredividedintotheephrin-A(EFNA)classandtheephrin-B(EFNB)class,basedontheirstructuresandsequencerelationships.TheEphrinsfromtheEFNAclassareanchoredtothemembranebyaglycosylphosphatidylinositollinkage,whiletheothersfromtheEFNBclassaretransmembraneproteins.
Description
EFNA3HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining434aminoacids(23-214aa)andhavingamolecularmassof48.7kDaEFNA3isfusedtoa242aminoacidhIgG-His-TagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
TheFractalkinesolution(0.5mg/ml)contains10%GlycerolandPhosphateBufferedSaline(pH7.4).
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
SafetyDataSheet
SDS