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Prospec/Bartonella SucB/Bartonella Henselae SucB Recombinant/1mg/PRO-2570-1mg-1mg
Cataloguenumber
PRO-2570
Introduction
NumerousformsofBartonellosisarecausedbyBartonellahenselaeaswellasCatScratchDisease&BacillaryAngiomatosis.Ithasbeenfoundthatupto95%ofpatientswithCatScratchDiseaseshowantibodiesagainstBartonellahenselaeantigens.HighlyimmunoreactiveproteinswhichareproducedbytheBartonellahenselaearethemostimportantantigensusedforthediagnosisofCatScratchDisease.Theimmunogenicproteindihydrolipoamide-succinyltransferasealsonamedSucBisanenzymeofthealpha-ketoglutaratedehydrogenasecomplex,whichcatalyzesthetransportofasuccinylgroupfromtheS-succinyldihydrolipoylmoietytocoenzymeA.
Description
RecombinantBartonellaHenselaeSucBproducedinE.Coliisasingle,non-glycosylatedpolypeptidechainhavingamolecularmassof45kDa.
BartonellaSucBisexpressedwitha-10xHistagatN-terminusandpurifiedbyproprietarychromatographictechniques.
Source
EscherichiaColi.
PhysicalAppearance
Formulation
BartonellaSucBissuppliedata20mMHEPESbufferpH-7.6,150mMNaCland40%Sucrose(w/v).
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan80%asdeterminedbySDS-PAGE.
SafetyDataSheet
SDS