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主营:主营:重组和天然蛋白、细胞因子和生长因子、趋化因子、蛋白激酶、激素和酶、热休克蛋白、病毒抗原、单克隆及多克隆抗体。
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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Prospec/ATP6AP2人/ATPase转运溶酶体辅蛋白2人重组/1mg/PRO-1599-1mg-1mg
商品详细Prospec/ATP6AP2人/ATPase转运溶酶体辅蛋白2人重组/1mg/PRO-1599-1mg-1mg
Prospec/ATP6AP2人/ATPase转运溶酶体辅蛋白2人重组/1mg/PRO-1599-1mg-1mg
Prospec/ATP6AP2人/ATPase转运溶酶体辅蛋白2人重组/1mg/PRO-1599-1mg-1mg
商品编号: PRO-1599-1mg-1mg
品牌: prospecbio
市场价: ¥104000.00
美元价: 44200.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

PRO-1599

Synonyms

Renin receptor, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, ER-localized type I transmembrane adaptor, Embryonic liver differentiation factor 10, N14F, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9, ATP6M8-9, V-ATPase M8.9 subunit, ATP6AP2, ATP6IP2, CAPER, ELDF10, M8-9, MRXE, XMRE, XPDS, HT028, MRXSH, MSTP009, APT6M8-9.

Introduction

ATPase Transporting Lysosomal Accessory Protein 2 (ATP6AP2) is a protein associated with triphosphatases (ATPases). Proton-translocating ATPases have vital roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. ATP6AP2 is linked with the transmembrane sector of the V-type ATPases, which have a transmembrane proton-conducting sector and an extramembrane catalytic sector. ATP6AP2 serves as a renin and prorenin cellular receptor; it mediates renin-dependent cellular responses by activating ERK1 and ERK2. ATP6AP2 is expressed in the brain, heart, placenta, liver, kidney and pancreas. ATP6AP2 is hardly detectable in the lung and skeletal muscles. ATP6AP2 is also expressed in the vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.

Description

ATP6AP2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 296 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 33kDa (calculated).

Source

Escherichia Coli.

Physical Appearance

Filtered White lyophilized (freeze-dried) powder.

Formulation

ATP6AP2 filtered (0.4 µm) and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5.

Solubility

It is recommended to add 200µl deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. ATP6AP2 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Stability

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Purity

Greater than 90.0% as determined by SDS-PAGE.

Amino acid sequence

MKHHHHHHAS NEFSILKSPG SVVFRNGNWP IPGERIPDVA ALSMGFSVKE DLSWPGLAVG NLFHRPRATV MVMVKGVNKL ALPPGSVISY PLENAVPFSL DSVANSIHSL FSEETPVVLQ LAPSEERVYM VGKANSVFED LSVTLRQLRN RLFQENSVLS SLPLNSLSRN NEVDLLFLSE LQVLHDISSL LSRHKHLAKD HSPDLYSLEL AGLDEIGKRY GEDSEQFRDA SKILVDALQK FADDMYSLYG GNAVVELVTV KSFDTSLIRK TRTILEAKQA KNPASPYNLA YKYNFE.

Safety Data Sheet

SDS

Usage

Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.