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当前位置: 首页 > 产品中心 > Bacterial_antigen > Prospec/HTLV-1 mosaic/HTLV-1 Mosaic Recombinant/500µg/HIV-144-500µg-500µg
商品详细Prospec/HTLV-1 mosaic/HTLV-1 Mosaic Recombinant/500µg/HIV-144-500µg-500µg
Prospec/HTLV-1 mosaic/HTLV-1 Mosaic Recombinant/500µg/HIV-144-500µg-500µg
Prospec/HTLV-1 mosaic/HTLV-1 Mosaic Recombinant/500µg/HIV-144-500µg-500µg
商品编号: HIV-144-500µg-500µg
品牌: prospecbio
市场价: ¥12000.00
美元价: 5100.00
产地: 美国(厂家直采)
公司:
产品分类: 细菌抗原
公司分类: Bacterial_antigen
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

HIV-144

Introduction

Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

Description

The E.Coli derived recombinant mosaic protein contains the gp21 and gp46 immunodominant regions, 374-400 amino acids and 190-207 amino acids, the MW is 42kDa. The protein is fused with GST at N-terminus.

Purification Method

HTLV-1 Mosaic was purified by proprietary chromatographic technique.

Purity

HTLV-1 Mosaic protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.

Formulation

60mM NaCl, 50mM Tris-HCl pH 8.0, 0.25% Sarkosil, 50% glycerol and 10mM glutathione.

Stability

HTLV-1 Mosaic although stable at 4°C for 1 week, should be stored below -18°C.Please prevent freeze thaw cycles.

Specificity

Immunoreactive with all sera of HTLV-I and HTLV-II infected individuals with antibody response to HTLV envelope.

Applications

HTLV-1 Mosaic can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.