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Prospec/HSV-2 gD (525-578) /Herpes Simplex Virus-2 gD (525-578 a.a.) Recombinant/100µg/HSV-229-100µg-100µg
Cataloguenumber
HSV-229
Introduction
ReceptorsacrossthecellmembraneinteractwithsomeviralglycoproteinsthereforenablingHSVtoenterthehostcell.TheHSVenterthroughporescreatedbythebindingofparticularreceptorsacrossthecellmembranewiththevirus"scoatingenvelope,followingbyafusionoftheHSVandthehostcell.HSVentersthehostcellthroughthesamemechanismandstagesasothervirusesdo.Initially,matchingreceptorsacrossthevirus"senvelopeandhostcell"smembraneinteractsandbringthetwotogether.Duringthetransitionalstage,beginsfusionbetweenthehostcellandvirus(hemifusionstate).Theclosingstagehappenswhenasteadyporewasmade;throughtheseporesthevirus"sparticlesenterthecell.
Description
TheE.ColiderivedrecombinantproteincontainstheHSV-2gD(525-578)immunodominantregion.HSV2gDisfusedtoasixhistidinehistagatc-terminusandpurifiedbyproprietarychromatographictechniques.
Source
Purity
Proteinis>95%pureasdeterminedbySDS-PAGE
PhysicalAppearance
Formulation
(1mg/ml)in1xPBS
StABIlity
HSV-2gDalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.
Pleasepreventfreezethawcycles.
Applications
ELISA&WB.
SafetyDataSheet
SDS