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Prospec/FLT1 D3 Human/Vascular Endothelial Growth Factor Receptor-1 D3 Human Recombinant/10µg/PKA-234-10µg-10µg
Cataloguenumber
PKA-234
Synonyms
Introduction
Description
FLT1D1-3HumanRecombinantproducedinbaculovirusismonomeric,glycosylated,polypeptidecontaining327aminoacidsandhavingamolecularmassof45kDa.Thesolublereceptorproteincontainsonlythefirst3extracellulardomains,whichcontainalltheinformationnecessaryforbindingofVEGF.TheFLT1ispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
FLT1D1-3waslyophilizedfromaconcentrated(1mg/ml)sterilesolutioncontaining1xPBS.
Solubility
StABIlity
LyophilizedFLT-1althoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionFLT1shouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
BiologicalActivity
TheactivityofFLT1D1-3wasdeterminedbyitsabilitytoinhibittheVEGF-165-inducedproliferationofHUVEcells.
Aminoacidsequence
SKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSY.
SafetyDataSheet
SDS