Cataloguenumber
ENZ-142
Synonyms
Phosphoribosyltransferasedomain-containingprotein1,PRTFDC1,HHGP.
Introduction
Phosphoribosyltransferasedomain-containingprotein1(PRTFDC1)isamemberofthepurine/pyrimidinephosphoribosyltransferasefamily.PRTFDC1hasalow,barelymeasurablephosphoribosyltransferaseactivity(invitro).PRTFDC1canbindGMP,IMPandalpha-D-5-phosphoribosyl1-pyrophosphate(PRPP).PRTFDC1isnotexpectedtoimpactpurinemetabolismorGMPsalvage.
Description
PRTFDC1producedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining248aminoacids(1-225a.a.)andhavingamolecularmassof28.1kDa.PRTFDC1isfusedtoa23aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
PRTFDC1proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),40%glycerol,0.1MNaCland1mMDTT.
StABIlity
PRTFDC1HumanRecombinantalthoughstableat4°Cfor1week,shouldbestoredbelow-18°C.Pleasepreventfreezethawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSMAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV.
SafetyDataSheet
SDS