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Prospec/NAA10 Human/N Alpha-Acetyltransferase 10, NatA Catalytic Subunit Human Recombinant/1mg/ENZ-158-1mg-1mg
Cataloguenumber
ENZ-158
Synonyms
N-alpha-acetyltransferase10,N-terminalacetyltransferasecomplexARD1subunithomologA,NatAcatalyticsubunit,NAA10,ARD1,ARD1A,TE2,NATD,DXS707.
Introduction
NAA10isamemberoftheacetyltransferasefamily.NAA10interactswithNAA15,HIF-1andwiththeribosome.InitsbindingtoHIF-1,NAA10functionsasaproteinacetyltransferasebyregulatingitsstABIlity.Invariouscelllines,NAA10isdownregulatedinresponsetohypoxia.NAA10isexpressedduringthecourseofthedevelopmentofthebrain.
Description
NAA10HumanRecombinantproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining255aminoacids(1-235a.a.)andhavingamolecularmassof28.6kDa(themolecularweightonSDS-PAGEwillappearhigher).NAA10isfusedtoa20aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
NAA10proteinsolution(1mg/ml)containing20mMTris-HClbuffer(pH8.0),5mMDTT,10%glyceroland200mMNaCl.
Stability
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS.
SafetyDataSheet
SDS