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Prospec/BLVRB Mouse/Biliverdin Reductase B Mouse Recombinant/1µg/ENZ-1074-1µg-1µg
Cataloguenumber
ENZ-1074
Synonyms
Flavinreductase(NADPH),FR,BiliverdinreductaseB,BVR-B,Biliverdin-IXbeta-reductase,NADPH-dependentdiaphorase,NADPH-flavinreductase,FLR.
Introduction
BLVRB(EC1.3.1.24)catalyzeselectrontransferfromreducedpyridinenucleotidestoflavinsaswellasmethyleneblue,pyrroloquinolinequinone,riboflavin,ormethemoglobin.BLVRBisinvolvedinprotectingcellsfromoxidativedamageorinregulatingironmetabolism.BLVRBconvertsbiliverdintobilirubinintheliver,convertingadouble-bondbetweenthesecondandthirdpyrroleringintoasingle-bond.BLVRBplaysaroleasinhumanerythrocytichemecatabolicpathwayandmostmammalianspecies.Biliverdinreductaseisabundantlyexpressedinkidney,spleen,liverandbrainaswellasatlowerlevelsinthethymusandminimallevelsbeingdetectedintestis.
Description
BLVRBMouseRecombinantproducedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining229aminoacids(1-206a.a)andhavingamolecularmassof24.6kDa.BLVRBisfusedtoa23aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
BLVRBproteinsolution(0.5mg/ml)containing20mMTris-HClbuffer(pH8.0)containing10%glycerol.
StABIlity
Purity
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSMTVKKIAIFGATGRTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVRQAADVDKTVAGQEAVIVLLGTGNDLSPTTVMSEGTRNIVTAMKAHGVDKVVACTSAFLLWDPTKVPPRLQDVTDDHIRMHKILQESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTNEYDGHTTYPSHQYD.
SafetyDataSheet
SDS