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Prospec/TRIB3 Human/Tribbles Pseudokinase 3 Human Recombinant/1mg/PKA-070-1mg-1mg
Prospec/TRIB3 Human/Tribbles Pseudokinase 3 Human Recombinant/1mg/PKA-070-1mg-1mg
商品编号：
PKA-070-1mg-1mg
品牌：
prospecbio
市场价：
¥104000.00
美元价：
44200.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PKA-070
Synonyms
Cell Growth Regulator With EF-Hand Domain 1, Cell GrowthRegulatory Gene 11 Protein, Hydrophobestin, CGR11, Cell Growth Regulator WithEF Hand Domain Protein 1, Cell Growth Regulator With EF Hand Domain 1, Tribbleshomolog 3.
Introduction
Tribbles Pseudokinase 3, also known as TRIB3, is a putative proteinkinase which is induced by the transcription factor NF-kappaB. In addition,TRIB3 is a negative regulator of NF-kappaB, and can as well sensitize cells toTNF- and TRAIL-induced apoptosis. Furthermore, TRIB3 is able to negativelyregulate the cell survival serine-threonine kinase AKT1. One of the diseaseswhich are associated with TRIB3 is anoxia.
Description
TRIB3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 381 amino acids (1-358 a.a) andhaving a molecular mass of 42.0kDa.
TRIB3 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
TRIB3 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMRATPLA APAGSLSRKK RLELDDNLDT ERPVQKRARS GPQPRLPPCLLPLSPPTAPD RATAVATASR LGPYVLLEPE EGGRAYQALH CPTGTEYTCK VYPVQEALAV LEPYARLPPHKHVARPTEVL AGTQLLYAFF TRTHGDMHSL VRSRHRIPEP EAAVLFRQMA TALAHCHQHG LVLRDLKLCRFVFADRERKK LVLENLEDSC VLTGPDDSLW DKHACPAYVG PEILSSRASY SGKAADVWSL GVALFTMLAGHYPFQDSEPV LLFGKIRRGA YALPAGLSAP ARCLVRCLLR REPAERLTAT GILLHPWLRQ DPMPLAPTRSHLWEAAQVVP DGLGLDEARE EEGDREVVLY G.
Safety Data Sheet
SDS
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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