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Prospec/AKT1 Human/Protein Kinase B Alpha Human Recombinant/1mg/PKA-068-1mg-1mg
Prospec/AKT1 Human/Protein Kinase B Alpha Human Recombinant/1mg/PKA-068-1mg-1mg
商品编号：
PKA-068-1mg-1mg
品牌：
prospecbio
市场价：
¥54000.00
美元价：
22950.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PKA-068
Synonyms
V-Akt Murine Thymoma Viral Oncogene Homolog 1, ProteinKinase B Alpha, Proto-Oncogene C-Akt, RAC-PK-Alpha, EC 2.7.11.1, PKB Alpha, CWS6,PKB, RAC, RAC-Alpha Serine/Threonine-Protein Kinase, Rac Protein Kinase Alpha,Protein Kinase B, PKB-ALPHA, RAC-ALPHA, EC 2.7.11, AKT1m, PRKBA, AKT, RAC-alphaserine/threonine-protein kinase.
Introduction
Akt1, also known as Akt or else protein kinase B (PKB) is an importantmolecule in mammaliancellular signaling. In humans, there are three genes inthe "Akt family": Akt1, Akt2, and Akt3. Moreover, these enzymes aremembers of the serine/threonine-specific protein kinase family (EC2.7.11.1). Akt1is involved in cellular survival pathways, by inhibiting apoptoticprocesses.Akt1 is also able to induce protein synthesis pathways, and is therefore a keysignaling protein in the cellular pathways which lead to skeletal musclehypertrophy, and general tissue growth. Since it can block apoptosis, andthereby promote cell survival, Akt1 has been implicated as a most importantfactor in numerous types of cancer. Akt (now also called Akt1) was at firstidentified as the oncogenein the transforming retrovirus, AKT8.
Description
AKT1 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 503 amino acids (1-480 a.a) and having a molecularmass of 58.1kDa.
AKT1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
AKT1protein solution (0.5mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMSDVAIV KEGWLHKRGE YIKTWRPRYF LLKNDGTFIG YKERPQDVDQREAPLNNFSV AQCQLMKTER PRPNTFIIRC LQWTTVIERT FHVETPEERE EWTTAIQTVA DGLKKQEEEEMDFRSGSPSD NSGAEEMEVS LAKPKHRVTM NEFEYLKLLGKGTFGKVILV KEKATGRYYA MKILKKEVIV AKDEVAHTLT ENRVLQNSRHPFLTALKYSF QTHDRLCFVM EYANGGELFF HLSRERVFSE DRARFYGAEI VSALDYLHSE KNVVYRDLKLENLMLDKDGH IKITDFGLCK EGIKDGATMK TFCGTPEYLA PEVLEDNDYG RAVDWWGLGVVMYEMMCGRL PFYNQDHEKL FELILMEEIR FPRTLGPEAK SLLSGLLKKDPKQRLGGGSE DAKEIMQHRF FAGIVWQHVY EKKLSPPFKP QVTSETDTRY FDEEFTAQMI TITPPDQDDSMECVDSERRP HFPQFSYSAS GTA.
Safety Data Sheet
SDS
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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