>
产品中心 >
Other_enzymes >
Prospec/PPP1CC Human, Active/Protein Phosphatase 1, Catalytic Subunit Gamma Human Recombinant, Active/50µg/ENZ-1042-50µg-50µg
Cataloguenumber
ENZ-1042
Synonyms
Proteinphosphatase1catalyticsubunitgammaisozyme/isoform,Proteinphosphatase1Ccatalyticsubunit,serine/threoninephosphatase1gamma,serine/threonine-proteinphosphatasePP1-gammacatalyticsubunit,PP1gamma,PPP1G,EC3.1.3.16.
Introduction
PPP1CCisvitalforcelldivisionandtakespartintheregulationofproteinsynthesis,musclecontractilityandglycogenmetabolism.Additionally,PPP1CChasaroleinlong-termsynapticplasticityandregulationofionicconductance,andhasasignificantroleindephosphorylatingsubstratessuchasthepostsynapticdensity-associatedCa2+/calmodulindependentproteinkinaseII.
Description
PPP1CCproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining343aminoacids(1-323a.a.)andhavingamolecularmassof39.1kDa.PPP1CCisfusedtoa20aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
ThePPP1CCproteinsolution(0.25mg/ml)containing20mMTris-HClbuffer(pH8.0),0.2MNaCl,2mMDTTand50%glycerol.
StABIlity
Purity
Greaterthan85.0%asdeterminedbySDS-PAGE.
BIOLOGicalActivity
Specificactivityis>700units/mg,andisdefinedastheamountofenzymethathydrolyzes1.0nmoleofp-nitrophenylphosphate(pNPP)perminuteatpH7.5at37°C.
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK.
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
