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Prospec/ACP5 Human/Acid Phosphatase-5 Human Recombinant/100µg/ENZ-1025-100µg-100µg
Cataloguenumber
ENZ-1025
Synonyms
AcidPhosphatase5,TartrateResistant,Tartrate-ResistantAcidATPase,HumanPurpleAcidPhosphatase,EC3.1.3.2,TrATPase,Tartrate-ResistantAcidPhosphataseType5,Tartrate-ResistantAcidPhosphatase5a,Tartrate-ResistantAcidPhosphatase5b,Tartrate-ResistantAcidPhosphatase,Type5AcidPhosphatase,TRACP5a,TRACP5b,TR-AP,HPAP,TRAP,ACP5.
Introduction
Tartrate-resistantacidphosphatasetype5(ACP5)isinvolvedinosteopontinandbonesialoproteindephosphorylation.ACP5isanironcontainingglycoproteinwhichcatalyzestheconversionoforthophosphoricmonoestertoalcoholandorthophosphate.ACP5expressionseemstoincreaseinsomepathologicalstatessuchasGaucherandHodgkindiseases,thehairycell,theB-cell,andtheT-cellleukemias.ACP5isthemostbasicoftheacidphosphatasesandistheonlyformnotinhibitedbyL(+)-tartrate.
Description
Source
PhysicalAppearance
Formulation
ACP5proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
BIOLOGicalActivity
Specificactivityis>10,000units/mg,andisdefinedastheamountofenzymethathydrolyze1.0nmolesofp-nitrophenylphosphate(pNPP)perminuteatpH5.0at37°C.
Aminoacidsequence
ATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP.
SafetyDataSheet
SDS