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Prospec/CLPP Human/ClpP Caseinolytic Peptidase Human Recombinant/10µg/ENZ-115-10µg-10µg
Cataloguenumber
ENZ-115
Synonyms
PutativeATP-dependentClpproteaseproteolyticsubunitmitochondrial,EndopeptidaseClp,CLPP.
Introduction
ATP-dependentClpproteaseproteolyticsubunit(CLPP)isamemberofthepeptidasefamilyS14.CLPPcleavespeptidesinavarietyofproteinsinamannerwhichrequiresATPhydrolysis.CLPPbeingthecatalyticcoreoftheClpproteolyticcomplexiscommonlyinvolvedinmanycellularprocessesviatheregulationofintracellularproteinquality.CLPPisresponsIBLeforasomewhatgeneralandcentralhousekeepingfunctionratherthanforthedegradationofspecificsubstrates.
Description
CLPPproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining222aminoacids(57-277a.a.)andhavingamolecularmassof24.2kDa.CLPPispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
Aminoacidsequence
MPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
SafetyDataSheet
SDS