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Prospec/KLK11 Human, Sf9/Kallikrein-11, 4 Human Recombinant, Sf9/1mg/ENZ-1089-1mg-1mg
Cataloguenumber
ENZ-1089
Synonyms
Kallikrein-11isoform1,KLK11,PRSS20,TLSP.
Introduction
Kallikreinsareasubgroupofserineproteaseshavingvariousphysiologicalfunctions.Numerouskallikreinsareinvolvedincarcinogenesis.Kallikrein-11(KLK11)whichisamultifunctionalproteaseis1ofthe15kallikreinsubfamilymembersfoundinaclusteronchromosome19.KLK11cleavessyntheticpeptidesafterargininebutnotlysineresidues.
Description
KLK11producedinSf9Insectcellsisasingle,glycosylatedpolypeptidechaincontaining241aminoacids(19-250a.a.)andhavingamolecularmassof26.7kDa(MolecularsizeonSDS-PAGEwillappearatapproximately28-40kDa).KLK11isexpressedwitha9aminoacidHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Insectcells.
PhysicalAppearance
Formulation
KLK11proteinsolution(0.5mg/m)contains50mMTris-HCl(pH7.5),0.1MNaCl,2mMCaCl2and10%glycerol.
StABIlity
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADLETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNNHHHHHH.
SafetyDataSheet
SDS