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当前位置: 首页 > 产品中心 > Other_enzymes > Prospec/DCT Human/Dopachrome Tautomerase Human Recombinant/2µg/ENZ-874-2µg-2µg
商品详细Prospec/DCT Human/Dopachrome Tautomerase Human Recombinant/2µg/ENZ-874-2µg-2µg
Prospec/DCT Human/Dopachrome Tautomerase Human Recombinant/2µg/ENZ-874-2µg-2µg
Prospec/DCT Human/Dopachrome Tautomerase Human Recombinant/2µg/ENZ-874-2µg-2µg
商品编号: ENZ-874-2µg-2µg
品牌: prospecbio
市场价: ¥1000.00
美元价: 450.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

ENZ-874

Synonyms

L-dopachrome tautomerase (EC:5.3.3.12), DCT, DT, L-dopachromeDelta-isomerase Tyrosinase-related protein2, TRP-2, TRP2, TYRP2.

Introduction

Dopachrome Tautomerase also known as DCT,belongs to the tyrosinase family. DCT takes a significant part in the synthesisof the melanin pigment including tyrosinase (Tyr), tyrosinase-related protein 1(Tyrp1). Which are highly involved in eumelanin synthesis. The change among theeumelanin and the pheomelanin pathways is assumed to depend on the presence ofcysteine. Hence, in the lack of cysteine, dopaquinone, the product oftyrosinase action, is transformed to cyclodopa (leucodopachrome) and afterwardsto dopachrome (and DOPA).

Description

DCT Human Recombinant produced in Sf9 Insect cell is asingle, non-glycosylated polypeptide chain containing 455 amino acids (24-472aa.a)and having a molecular mass of 52.1kDa (Migrates at 50-70kDa on SDS-PAGE underreducing conditions). DCT is fused to a 6 amino acidHis tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9 Insect cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

STK3 protein solution (0.25mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by SDS-PAGE.

Amino acid sequence

QFPRVCMTVD SLVNKECCPRLGAESANVCG SQQGRGQCTE VRADTRPWSG PYILRNQDDR ELWPRKFFHR TCKCTGNFAG YNCGDCKFGW TGPNCERKKP PVIRQNIHSL SPQEREQFLG ALDLAKKRVH PDYVITTQHW LGLLGPNGTQ PQFANCSVYDFFVWLHYYSV RDTLLGPGRP YRAIDFSHQG PAFVTWHRYH LLCLERDLQR LIGNESFALP YWNFATGRNECDVCTDQLFG AARPDDPTLI SRNSRFSSWE TVCDSLDDYN HLVTLCNGTY EGLLRRNQMG RNSMKLPTLK DIRDCLSLQK FDNPPFFQNS TFSFRNALEG FDKADGTLDS QVMSLHNLVH SFLNGTNALP HSAANDPIFVVLHSFTDAIF DEWMKRFNPP ADAWPQELAP IGHNRMYNMV PFFPPVTNEE LFLTSDQLGY SYAIDLPVSVEETPGWPTTH HHHHH.

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.