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Prospec/GZMK Human, Sf9/Granzyme-K, Human Recombinant, sf9/2µg/ENZ-1031-2µg-2µg
Cataloguenumber
ENZ-1031
Synonyms
GZMK,TRYP2,Granzyme-K,GranzymeK,Fragmentin-3,Granzyme-3,NK-tryptase-2,NK-Tryp-2.
Introduction
GZMKisapartofagroupofrelatedserineproteasesfromthecytoplasmicgranulesofcytotoxiclymphocytes.CytolyticTlymphocytesandnaturalkillercellshavetheoutstandingABIlitytobind,recognizeandlysespecifictargetcells.Theydefendtheirhostbylysingcellsbearingontheirsurface"nonself"antigens,usuallypeptidesorproteinsresultingfrominfectionbyintracellularpathogens.
Description
GZMKHumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining247aminoacids(27-264)andhavingamolecularmassof26.9kDa(MolecularsizeonSDS-PAGEwillappearatapproximately28-40kDa).GZMKisfusedtoa6aminoacidIgGHis-TagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
GZMKproteinsolution(0.25mg/ml)containingPhosphateBufferedSaline(pH7.4),20%glyceroland1mMDTT.
Stability
Purity
Aminoacidsequence
ADPIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHTNHHHHHH.
SafetyDataSheet
SDS