商品介绍
Catalogue number
PRO-2270
Introduction
Streptococcus pyogenes is the cause of many significant human diseases, ranging from mild superficial skin infections to life-threatening systemic diseases. Infections usually begin in the throat or skin. The most conspicuous sign is a strawberry-like rash. Instances of mild S. pyogenes infections include pharyngitis (strep throat) and localized skin infection (impetigo). The invasion of S. pyogenes and its multiplication in the fascia can lead to necrotizing fasciitis, a life-threatening condition requiring surgery. Throat infections linked with the release of certain toxins lead to scarlet fever. Other toxigenic S. pyogenes infections may lead to potentially life-threatening streptococcal toxic shock syndrome. S. pyogenes may also cause disease in the form of post-infectious "nonpyogenic" (not associated with local bacterial multiplication and pus formation) syndromes. These autoimmune-mediated complications develop from a small percentage of infections and comprise rheumatic fever and acute post infectious glomerulonephritis. Acute glomerulonephritis (inflammation of the renal glomerulus) can arise from streptococcal pharyngitis or skin infection.
Description
Recombinant Streptococcus Pyogenes Arginine Deiminase produced in E.coli is a non-glycosylated, polypeptide chain having a calculated molecular mass of 47,829 Dalton. S.Pyogenes arcA is expressed with a 10xHis tag at N-terminus and purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
S.Pyogenes arcA is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Purity
Greater than 80.0% as determined by SDS-PAGE.
Immunological functions
1. Binds IgG- and IgM- and IgA-type human antibodies.2. Immunodot test with positive/negative sera panels.
Safety Data Sheet
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
