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Prospec/CTSZ Mouse, Active/Cathepsin-Z, Active Mouse Recombinant/50µg/ENZ-1108-50µg-50µg
Cataloguenumber
ENZ-1108
Synonyms
CathepsinZ,CathepsinX,Cysteine-TypeCarboxypeptidase,LysosomalCarboxypeptidaseB,CarboxypeptidaseLB,CathepsinB2,CathepsinIV,CathepsinZ1,CathepsinP,CathepsinY,EC3.4.18.1,PreprocathepsinP,CTSX.
Introduction
Cathepsin-Z(CTSZ)isalysosomalcysteineproteinaseandamemberofthepeptidaseC1family.CTSZ,whichisknownalsoascathepsinXandcathepsinP,exhibitscarboxy-monopeptidaseandcarboxy-dipeptidaseactivities.CTSZisexpressedubiquitouslyincancercelllinesandprimarytumorsandasothermembersofthisfamily,takespartintumOrigenesis.
Description
CTSZMouseRecombinantproducedinBaculovirusisasingle,glycosylated,polypeptidechaincontaining292aminoacids(23-306aa)andhavingamolecularmassof32.8kDa.CTSZisfusedtoa8aminoacidHistagatC-terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
TheCTSZsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
BIOLOGicalActivity
Specificactivityis>3,000pmol/min/ug.Oneunitwillconvert1pmoleofMca-PLGL-Dpa-AR-NH2toMCA-Pro-Leu-OHperminuteatpH3.5at25°C.
Aminoacidsequence
ARARLYFRSGQTCYHPIRGDQLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATEMMSNYTGGIYAEHQDQAVINHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRIVTSTYKGGTGDSYNLAIESACTFGDPIVLEHHHHHH
SafetyDataSheet
SDS