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Prospec/CTSZ Human, Sf9/Cathepsin-Z Human Recombinant, Sf9/50µg/ENZ-1097-50µg-50µg
Cataloguenumber
ENZ-1097
Synonyms
CathepsinZ,CathepsinX,Cysteine-TypeCarboxypeptidase,LysosomalCarboxypeptidaseB,CarboxypeptidaseLB,CathepsinB2,CathepsinIV,CathepsinZ1,CathepsinP,CathepsinY,EC3.4.18.1,PreprocathepsinP,CTSX.
Introduction
Cathepsin-Z(CTSZ)isalysosomalcysteineproteinaseandamemberofthepeptidaseC1family.CTSZ,whichisknownalsoascathepsinXandcathepsinP,exhibitscarboxy-monopeptidaseandcarboxy-dipeptidaseactivities.CTSZisexpressedubiquitouslyincancercelllinesandprimarytumorsandasothermembersofthisfamily,takespartintumOrigenesis.
Description
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Formulation
CTSZproteinsolution(0.5mg/ml)contains10%glycerol&PhosphateBufferedSaline(pH7.4).
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleaseavoidfreezethawcycles.
Purity
Greaterthan95%asdeterminedbySDS-PAGE.
BIOLOGicalActivity
Thespecificactivityisdetermentastheabilityof1unittoconvert1.0pmoleofMca-PLGL-Dpa-AR-NH2toMCA-Pro-Leu-OHperminuteatpH3.5at25Candis>1,400pmol/min/ug.
Aminoacidsequence
GLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIVLEHHHHHH
SafetyDataSheet
SDS