>
产品中心 >
Other_enzymes >
Prospec/ADK Mouse/Adenosine Kinase Mouse Recombinant/100µg/PKA-105-100µg-100µg
Cataloguenumber
PKA-105
Synonyms
AK,ADK,AdenosineKinase,Adenosine5-Phosphotransferase.
Introduction
AdenosineKinaseisanabundantenzymeinmammaliantissueswhichcatalyzesthetransferofthegamma-phosphatefromATPtoadenosine,thusisasaregulatorofconcentrationsofbothextracellularadenosineandintracellularadeninenucleotides.Adenosinehasextensiveeffectsonthecardiovascular,nervous,respiratory,andimmunesystemsandinhibitorsoftheenzymetakeacrucialpharmacologicalpartingrowingintravascularadenosineconcentrationsandactingasanti-inflammatoryagents.
Description
ADKproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining384aminoacids(1-361a.a.)andhavingamolecularmassof42.5kDa.ADKisfusedtoa23aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
TheADKproteinsolution(1mg/ml)contains20%glycerol,20mMTris-HClbuffer(pH8.0),1mMEDTA&50mMNaCl.
StABIlity
Purity
BIOLOGicalActivity
Specificactivityis>100pmol/min/andisdefinedastheamountofenzymethatconvert1.0pmoleofadenosinetoAMPperminuteatpH7.5at37CinacouplesystemwithPKandLDH.
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSMAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPDFH.
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.