
Cataloguenumber
HOR-272
Introduction
PMSGHormoneisawellknowusedhormonetogetherwithprogestogentoincreaseovulationjustbeforetoartificialinsemination.PMSGhormoneisaplacentalglycoproteinproducedfromtheserumofpregnantmares.PMSGcomprisesofanalfasubunitandabetasubunit.PMSGhormoneissecretedfromendometrialcupswithinthepregnantmareuterusagingfrom40to130daysintotheirmaturation,andonceextracted,itcanbeenusedtopromoteartificiallyestrusinfemaleanimals.TheseassembliesproducePMSGhormonetoinducemare"sovarianandrepsouctivestructures.PMSGcaninducethegrowthoffolliclesbyovariesandresultsinovulatation.PMSGhormonehasanabouta4dayhalf-lifeofbioactivityinspeciesotherthanhorses.TheextendedBIOLOGicalactivitycancauseovarianstimulationandovulation.However,PMSGusealoneoftencausescysticovariandiseasebecauseoftheunrestrainedovarianstimulationandduetothesugarmoleculeswhichdecreaseclearanceofthehormone.PMSGismorelikelytobeusedthanotherpituitaryhormonesduetotheextendedcirculatoryhalf-life.PMSGsolelyexhibitsluteinizinghormonelikeactivity,howeverinotheranimalclassesithasFSH&LHlikeactivity.
Description
PMSGisacomplexglycoproteinobtainedfromtheserumofpregnantmares.This43-63kdaproteiniscapableofsupplementingandbeingsubstitutedforthefolliclestimulatingandinterstitialcell-stimulatinghormoneoftheanteriorpituitaryglandinboththemaleandfemale.ThusPMSG-Intervetstimulatesdevelopmentoftheovarianfollicleinthefemale.
Source
PhysicalAppearance
Formulation
Solubility
StABIlity
SafetyDataSheet
SDS
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
References
1.Title:REPRODUCTIVECYCLICITYANDPROFILESINPOSTPARTUMRAMBOUILLETEWESTREATEDCONTAININGINTRAVAGINALINSERTANDPMSG.Publication:Proceedings,WesternSection,AmericanSocietyofAnimalScienceVol.62,2011Link:http://www.asas.org/docs/western-section/2011-western-section-proceedings.pdf?sfvrsn=47455f63_0
2.Title:CorrelationoftheMitochondrialActivityofTwo-CellEmbryosProducedInVitroandtheTwo-CellBlockInKunmingandB6C3F1Mice