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当前位置: 首页 > 产品中心 > human_antigen > Prospec/CD4 Human (125-202)/CD-4 (125-202 a.a.) Human Recombinant/20µg/CYT-315-20µg-20µg
商品详细Prospec/CD4 Human (125-202)/CD-4 (125-202 a.a.) Human Recombinant/20µg/CYT-315-20µg-20µg
Prospec/CD4 Human (125-202)/CD-4 (125-202 a.a.) Human Recombinant/20µg/CYT-315-20µg-20µg
Prospec/CD4 Human (125-202)/CD-4 (125-202 a.a.) Human Recombinant/20µg/CYT-315-20µg-20µg
商品编号: CYT-315-20µg-20µg
品牌: prospecbio
市场价: ¥2600.00
美元价: 1170.00
产地: 美国(厂家直采)
公司:
产品分类: 人体抗原
公司分类: human_antigen
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

CYT-315

Synonyms

gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.

Introduction

CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

Description

CD-4 Human Recombinant is fused with a 4kDa His Tag and encoding amino acids 125-202, having a total molecular weight of 19 kDa.

Source

Escherichia Coli.

Physical Appearance

Sterile lyophilized powder.

Formulation

Each mg contains 1X PBS.

Solubility

It is recommended to reconstitute the lyophilized CD-4 (125-202) in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.

Purity

Greater than 90% as determined by SDS-PAGE.

Applications

• Protein Assay. • Antibody Production. • Western Blotting.

References

Title:Reduced Monomeric CD4 Is the Preferred Receptor for HIV.Publication: 10.1074/jbc.M110.190579 December 24, 2010 The Journal of Biological Chemistry, 285, 40793-40799. Link:http://www.jbc.org/content/285/52/40793.full#fn-1

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.