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Prospec/CD23 Human, Sf9/CD23 Human Recombinant, Sf9/5µg/PRO-2499-5µg-5µg
Catalogue number
PRO-2499
Synonyms
Low affinity immunoglobulin epsilon Fc receptor isoform a, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF, C-type lectin domain family 4 member J, Immunoglobulin E-binding factor, Lymphocyte IgE receptor.
Introduction
FCER2, or Fc epsilon RII, is a receptor for IgE with low affinity, which is critical to regulation of IgE levels. IgE is an antibody isotype that attached to allergy and resistance to parasites. FCER2 is a C-type lectin, contrary to many of the receptors for antibodies. FCER2 is located on activated macrophages, mature B cells, follicular dendritic cells, platelets and eosinophils.
Description
FCER2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 283 amino acids (48-321a.a.) and having a molecular mass of 32.0kDa. (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).FCER2 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Physical Appearance
Formulation
FCER2 protein solution (0.25mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
Stability
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
ADPDTTQSLK QLEERAARNV SQVSKNLESH HGDQMAQKSQ STQISQELEE LRAEQQRLKS QDLELSWNLN GLQADLSSFK SQELNERNEA SDLLERLREE VTKLRMELQV SSGFVCNTCP EKWINFQRKC YYFGKGTKQW VHARYACDDM EGQLVSIHSP EEQDFLTKHA SHTGSWIGLRNLDLKGEFIW VDGSHVDYSN WAPGEPTSRS QGEDCVMMRG SGRWNDAFCD RKLGAWVCDR LATCTPPASE GSAESMGPDS RPDPDGRLPTPSAPLHSHHH HHH.
Safety Data Sheet
SDS