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Prospec/CD200R1 Human/CD200 Receptor 1 Human Recombinant/5µg/PRO-2548-5µg-5µg
Cataloguenumber
PRO-2548
Synonyms
CellsurfaceglycoproteinCD200receptor1isoformd,CD200R1,CD200R,HCRTR2,MOX2R,OX2R,CellsurfaceglycoproteinCD200receptor1,CD200cellsurfaceglycoproteinreceptor,CellsurfaceglycoproteinOX2receptor1,Cd200r1,Mox2r,Ox2r. |
Introduction
CD200R1,alsoknownascellsurfaceglycoproteinCD200receptor1,isanisoformofCD200receptorswhichisexpressedoncellsofthemyeloidlineage.CD200R1inhibitorysignalingpathwayhasbeeninvolvedintakingaprominentroleinlimitinginflammationinabroadrangeofinflammatorydiseases.CD200R1signalinginhibitstheexpressionofproinflammatorymoleculesincludingtumornecrosisfactor,interferons,inadditiontoinducIBLenitricoxidesynthaseinresponsetoselectedstimuli.
Description
CD200R1producedinSf9Insectcellsisasingle,glycosylatedpolypeptidechaincontaining462aminoacids(24-243a.a.)andhavingamolecularmassof51.9kDa(MolecularsizeonSDS-PAGEwillappearatapproximately50-70kDa).CD200R1isexpressedwith242aminoacidsHistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Sterilefilteredcolorlesssolution.
Formulation
CD200R1proteinsolution(0.25mg/ml)containsphosphatebufferedsaline(pH7.4)and10%glycerol. |
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
SafetyDataSheet
SDS
Aminoacidsequence
ADLSSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.