Cataloguenumber
PRO-2416
Synonyms
CD200,MOX1,MOX2,MRC,OX-2,CD200Molecule,CD200Antigen,AntigenIdentifiedByMonoclonalAntibodyMRCOX-2,OX-2MembraneGlycoprotein.
Introduction
CD200isatype-1membraneglycoproteinwhichisapartoftheimmunoglobulinsuperfamilyduetoits2immunoglobulindomains.CD200regulatesmyeloidcellactivityanddeliversaninhibitorysignalforthemacrophagelineageinvarioustissues.CD200isalsoCostimulatesT-cellproliferation.
Description
CD200HumanRecombinantproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechaincontaining444aminoacids(31-232a.a.)andhavingamolecularmassof49.7kDa(MolecularsizeonSDS-PAGEwillappearatapproximately57-70kDa).CD200isexpressedwitha242aminoacidhIgG-HistagatC-Terminusandpurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
CD200proteinsolution(0.5mg/ml)containsPhosphateBufferedSaline(pH7.4)and10%glycerol.
StABIlity
Purity
Greaterthan95.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
ADPQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH.
SafetyDataSheet
SDS