Prospec/CD1E Human/CD1E Human Recombinant/20µg/PRO-1907-20µg-20µg
商品编号：
PRO-1907-20µg-20µg
品牌：
prospecbio
市场价：
¥2600.00
美元价：
1170.00
产品分类：
人体抗原
公司分类：
human_antigen
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
PRO-1907
Synonyms
CD1A, R2, T-cell surface glycoprotein CD1e, membrane-associated, R2G1, sCD1e.
Introduction
CD1E belongs to the CD1family of transmembrane glycoproteins which are structurally associated to the mainMHC (histocompatibility complex) proteins and form heterodimers withbeta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipidand glycolipid antigens of self or microbial origin to T cells. The humangenome is comprised of 5 CD1 family genes organized in a cluster on chromosome1. The CD1 family members are belief to differ in their cellular localizationand specificity for particular lipid ligands. CD1E localizes within Golgicompartments, endosomes, and lysosomes, and is cleaved into a steady solubleform. The soluble form is necessary for the intracellular processing of someglycolipids into a form that can be presented by other CD1 family members.
Description
CD1E Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 297 amino acids (32-305 a.a) andhaving a molecular mass of 33.1kDa.CD1E is fused to a 23 amino acid His-tag at N-terminus &purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CD1E protein solution (1mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol and 0.4M Urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSEEQLSFR MLQTSSFANH SWAHSEGSGW LGDLQTHGWD TVLGTIRFLKPWSHGNFSKQ ELKNLQSLFQ LYFHSFIQIV QASAGQFQLE YPFEIQILAG CRMNAPQIFL NMAYQGSDFLSFQGISWEPS PGAGIRAQNI CKVLNRYLDI KEILQSLLGH TCPRFLAGLM EAGESELKRK VKPEAWLSCGPSPGPGRLQL VCHVSGFYPK PVWVMWMRGE QEQRGTQRGD VLPNADETWY LRATLDVAAG EAAGLSCRVKHSSLGGHDLI IHWGGYS.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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