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当前位置: 首页 > 产品中心 > Growth_factor > Prospec/催乳素羊/催乳素羊重组体/50µg/CYT-240-50µg-50µg
商品详细Prospec/催乳素羊/催乳素羊重组体/50µg/CYT-240-50µg-50µg
Prospec/催乳素羊/催乳素羊重组体/50µg/CYT-240-50µg-50µg
Prospec/催乳素羊/催乳素羊重组体/50µg/CYT-240-50µg-50µg
商品编号: CYT-240-50µg-50µg
品牌: prospecbio
市场价: ¥2600.00
美元价: 1170.00
产地: 美国(厂家直采)
公司:
产品分类: 生长因子
公司分类: Growth_factor
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Catalogue number

CYT-240

Synonyms

Mammotropin, Luteotropic hormone, Luteotropin, PRL.

Introduction

Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.

Description

Prolactin Ovine Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids and having a molecular mass of 23 kDa. The Prolactin n is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

The protein was lyophilized from a concentrated (1mg/ml) solution with 0.02-0.03% NaHCO3.

Solubility

It is recommended to reconstitute the lyophilized Prolactin in sterile 18MΩ-cm H2O or 0.4% NaHCO3 adjusted to pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prl should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Purity

Greater than 99.0% as determined by:(a)Gel filtration analysis.(b) Analysis by SDS-PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Pro-Val-Cys-Pro.

Biological Activity

Is fully biologically active as evidenced by inducing proliferation of Nb2 cells.

Protein content

Protein quantitation was carried out by UV spectroscopy at 280 nm using the absorbency value of 0.93 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC DNAman computer analysis program of protein sequences.

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Safety Data Sheet

SDS

References

1.Title:Prolactin Treatment Improves Engraftment and Function of Transplanted Pancreatic Islets.Publication:Published online before print December 18, 2008, doi: 10.1210/en.2008-1318 Endocrinology April 1, 2009 vol. 150 no. 4 1646-1653 .Link:http://endo.endojournals.org/content/150/4/1646.full2.Title:ISLET ENDOTHELIAL CELLS AND PANCREATIC ?-CELL PROLIFERATION: STUDIES IN VITRO AND DURING PREGNANCY IN ADULT RATS.Publication:Endocrinology. First published January 26, 2006 as doi:10.1210/en.2005-0997.<="">Link:http://endo.endojournals.org/content/early/2006/01/26/en.2005-0997.full.pdf3.Title:Prolactin Treatment Improves Engraftment and Function of Transplanted Pancreatic Islets.Publication:Endocrinology. First published ahead of print December 18, 2008 as doi:10.1210/en.2008-1318.Link:http://endo.endojournals.org/content/early/2008/12/18/en.2008-1318.full.pdf
4.Title:Islet Endothelial Cells and Pancreatic -Cell
Proliferation: Studies in Vitro and during Pregnancy in Adult Rats.
Publication:Published online before printJanuary 26, 2006, doi:10.1210/en.2005-0997Endocrinologyvol. 147no. 52315-2324.
Link:http://endo.endojournals.org/content/147/5/2315.full.pdf+html
品牌介绍
    ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作,1947年出生于以色列。1991-1997创建ReProGen 公司,从事细胞因子和趋化因子的大量生产及纯化;1997-2000创建ProSpec-TechnoGene,主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。       ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.       Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....       Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.       ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.