>
产品中心 >
Growth_factor >
Prospec/EGF Mouse, His Active/Epidermal Growth Factor, His Active Mouse Recombinant/50µg/CYT-1054-50µg-50µg
Cataloguenumber
CYT-1054
Synonyms
AI790464,Pro-epidermalgrowthfactor,URG.
Introduction
Pro-EpidermalGrowthFactorIsoform1orEGF,isaglobularpeptide(77aaresidues)whichincludesthreeintramoleculardisulfidebonds.Thisproteinactsasagrowthfactorthatmediatesthegrowthandproliferationofdifferentepithelial&epidermalcells.AmongotherprocessesthatEGFispartofareinhibitionofgastricsecretionandwoundhealing.EGFisaligandforclassItyrosinekinasereceptor(c-erbB).
Description
EGFMouseRecombinantproducedinE.Coliisasingle,non-glycosylatedpolypeptidechaincontaining77aminoacids(977-1029a.a)andhavingamolecularmassof8.6kDa.EGFisfusedtoa24aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
EGFproteinsolution(0.25mg/ml)contains10%glycerol,20mMTris-HCl(pH8.0),0.1MNaCl&2mMDTT.
StABIlity
Purity
BIOLOGicalActivity
MeasuredinacellproliferationassayusingmouseBalb/3T3cell.TheED50forthiseffectlessorequalto1ng/ml.
Aminoacidsequence
MGSSHHHHHHSSGLVPRGSHMGSMNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELR.
SafetyDataSheet
SDS