Prospec/TNF a Human, Sf9/Tumor Necrosis Factor-alpha Human Recombinant, Sf9/2µg/CYT-903-2µg-2µg
商品编号：
CYT-903-2µg-2µg
品牌：
prospecbio
市场价：
¥1000.00
美元价：
450.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Catalogue number
CYT-903
Synonyms
Tumor Necrosis Factor, TNFA, Tumor Necrosis Factor LigandSuperfamily Member 2, Cachectin, TNF-Alpha, TNFSF2, TNF-A, Tumor Necrosis Factor(TNF Superfamily, Member 2), Tumor Necrosis Factor-Alpha, TNF,Macrophage-Derived, TNF, Monocyte-Derived, TNF Superfamily, APC1 Protein,Member 2, DIF, Tumor necrosis factor.
Introduction
Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF"s primary role is in the regulation of immune cells.Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.
Description
TNF a produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 163 amino acids (77-233a.a.) andhaving a molecular mass of 18.1kDa.
(Molecular size on SDS-PAGE will appear atapproximately 18-28kDa).
TNF a is expressed with a 6amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.
Source
Sf9,Baculovirus cells.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TNF a protein solution (1mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity
Greater than 90.0% as determined bySDS-PAGE.
Biological Activity
Measured in a cytotoxicity assay using L929 mouse fibrosarcomacells in the presence of the metabolic inhibitor actinomycin D.
The ED50 for this effect is ≤ 0.2 ng/ml.
Amino acid sequence
VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVVPSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYLGGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIALHHH HHH.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
品牌介绍
ProSpec-Tany TechnoGene Ltd.公司创立人Dr. Tanchum (Tany) Amarant 主要致力于蛋白生物化学方面的研究工作，1947年出生于以色列。1991-1997创建ReProGen 公司，从事细胞因子和趋化因子的大量生产及纯化；1997-2000创建ProSpec-TechnoGene，主要生产用于生命科学研究的各种重组蛋白及相关抗体。拥有专利United States Patent 5434135。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
Our research team and scientists have been able to assemble more than 1700 recombinant proteins, peptides and antibodies for your research needs. The proteins are rigorously tested to meet the research and development demand for excellent quality, uncompromising biological activity at competitive prices.
ProSpec has established sterling reputation among the scientific community, a reputation built on innovative products, customer service and attention to detail. Our reputation for quality is an essential factor in achieving a favorable position in the market place and the benefits associated with manufacturing top quality products.
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