
Cataloguenumber
CYT-359
Synonyms
ImmuneIFN,typeIIIFN,TcellIFN,MAF,IFNG,IFG,IFI,IFN-gamma.
Introduction
IFN-gammaproducedbylymphocytesactivatedbyspecificantigensormitogens.IFN-gamma,inadditiontohavingantiviralactivity,hasimportantimmunoregulatoryfunctions,itisapotentactivatorofmacrophages,andhasantiproliferativeeffectsontransformedcellsanditcanpotentiatetheantiviralandantitumoreffectsofthetypeIIFNs.
Description
IFN-gammaRatRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining135aminoacidsandhavingamolecularmassof15609Dalton.TheIFN-gammaispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
Solubility
ItisrecommendedtoreconstitutethelyophilizedIFN-gammainsterile18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.
StABIlity
LyophilizedIFN-gammaalthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionIFN-gammashouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.
Purity
Aminoacidsequence
BIOLOGicalActivity
SafetyDataSheet
SDS