
Cataloguenumber
CYT-234
Synonyms
LeukocyteIFN,BcellIFN,TypeIIFN,IFNB1,IFB,IFF,IFNB,IFN-b1b,MGC96956.
Introduction
IFN-beta1bhasantiviral,antibacterialandanticanceractivities.
Description
IFNbeta1bHumanRecombinantproducedinE.Coliisasingle,non-glycosylatedmutein(variantform)ofhumanIFNbeta-1bpolypeptidechaincontaining165aminoacidsandhavingamolecularmassof18510.86Dalton.TheIFN-betagenewasclonedfromhumanfibroblastsandalteredtosubstituteSerinefortheCysteineresiduefoundatposition17.IFNbeta-1bispurifiedbyproprietarychromatographictechniques.
Source
PhysicalAppearance
Formulation
Solubility
ItisrecommendedtoreconstitutethelyophilizedIFNbeta-1binsterile18M-cmH2Oataconcentrationof0.25mg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.
StABIlity
LyophilizedIFN-beta1balthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionIFNB1bshouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.Pleasepreventfreeze-thawcycles.
Purity
Aminoacidsequence
BIOLOGicalActivity
Proteincontent
SafetyDataSheet
SDS